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Airntm2.1Dpb
Targeted Allele Detail
Summary
Symbol: Airntm2.1Dpb
Name: antisense Igf2r RNA; targeted mutation 2.1, Denise P Barlow
MGI ID: MGI:5426385
Synonyms: TDRdelta
Gene: Airn  Location: Chr17:12960198-13078771 bp, + strand  Genetic Position: Chr17, 8.66 cM
Alliance: Airntm2.1Dpb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:183397
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe sequence encoding the tandem direct repeats (TDRs) were deleted. Cre-mediated recombination removed the upstream floxed neo cassette. (J:183397)
Generation of the Airntm2.1Dpb allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Airn Mutation:  4 strains or lines available
Notes
ES cell line = S12 (modified D3; 129S2/SvPas)
References
Original:  J:183397 Koerner MV, et al., A downstream CpG island controls transcript initiation and elongation and the methylation state of the imprinted Airn macro ncRNA promoter. PLoS Genet. 2012 Mar;8(3):e1002540
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory