Arhgef25^tm1.1Xya
Targeted Allele Detail

Summary

• Symbol: Arhgef25^tm1.1Xya
• Name: Rho guanine nucleotide exchange factor 25; targeted mutation 1.1, Xiao Yang
• MGI ID: MGI:5426693
• Synonyms: Geft^fl
• Gene: Arhgef25 Location: Chr10:127018394-127025952 bp, - strand Genetic Position: Chr10, 74.5 cM, cytoband D3
• Alliance: Arhgef25^tm1.1Xya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183551
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 17. Flp-mediated recombination removed the neo cassette and left exons 5 through 17 floxed. (J:183551)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgef25 Mutation: 37 strains or lines available

References

• Original: J:183551 Fan X, et al., Geft is dispensable for the development of the second heart field. BMB Rep. 2012 Mar;45(3):153-8
• All: 1 reference(s)