Abcb6^tm1Jsch
Targeted Allele Detail

Summary

• Symbol: Abcb6^tm1Jsch
• Name: ATP-binding cassette, sub-family B member 6; targeted mutation 1, John D Schuetz
• MGI ID: MGI:5426703
• Gene: Abcb6 Location: Chr1:75148361-75157036 bp, - strand Genetic Position: Chr1, 38.62 cM, cytoband C3
• Alliance: Abcb6^tm1Jsch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184574
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Exons 13 and 14 were replaced with a neo cassette via homologous recombination. (J:184574)

Generation of the Abcb6^tm1Jsch allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abcb6 Mutation: 41 strains or lines available

References

• Original: J:184574 Ulrich DL, et al., ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity. J Biol Chem. 2012 Apr 13;287(16):12679-90
• All: 3 reference(s)