Del(1Fcgr2b-Fcgr3)1Rav
Targeted Allele Detail

Summary

• Symbol: Del(1Fcgr2b-Fcgr3)1Rav
• Name: deletion, Chr 1, Jeffrey V Ravetch 1
• MGI ID: MGI:5426827
• Synonyms: Del1Rav, FcRalpha^-
• Gene: Del(1Fcgr2b-Fcgr3)1Rav Location: Chr1:170788127-170892504 bp Genetic Position: Chr1, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183615
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intergenic deletion, Intragenic deletion Del(1Fcgr2b-Fcgr3)1Rav involves 13 genes/genome features (Fcgr2b, Gm10522, Fcgr4 ...) View all Mutation details: Cre-mediated recombination between Fcgr2b and Fcgr3 removed the 95 kb intervening sequence, including Fcgr4. (J:183615)

Generation of the Del(1Fcgr2b-Fcgr3)1Rav deletion

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(1Fcgr2b-Fcgr3)1Rav Mutation: 0 strains or lines available

References

• Original: J:183615 Smith P, et al., Mouse model recapitulating human Fcgamma receptor structural and functional diversity. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6181-6
• All: 12 reference(s)