Irf6^tm1Pts
Targeted Allele Detail

Summary

• Symbol: Irf6^tm1Pts
• Name: interferon regulatory factor 6; targeted mutation 1, Paul T Sharpe
• MGI ID: MGI:5426868
• Synonyms: Irf6^neo
• Gene: Irf6 Location: Chr1:192835419-192854331 bp, + strand Genetic Position: Chr1, 97.6 cM
• Alliance: Irf6^tm1Pts page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184926
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, Hypomorph)
• Mutation: Insertion
• Mutation details: LoxP sites and a neo cassette were inserted into the gene to create a conditionally targeted allele. This allele is hypomorphic. (J:184926)

Expression

In Mice Carrying this Mutation:

9 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Irf6 Mutation: 26 strains or lines available

References

• Original: J:184926 Blackburn J, et al., The role of Irf6 in tooth epithelial invagination. Dev Biol. 2012 May 1;365(1):61-70
• All: 3 reference(s)