Tg(KRT5-CHUK)#Rche
Transgene Detail

Summary

• Symbol: Tg(KRT5-CHUK)#Rche
• Name: transgene insertion, Ellen Richie
• MGI ID: MGI:5426890
• Synonyms: K5-IKKalpha
• Transgene: Tg(KRT5-CHUK)#Rche Location: unknown
• Alliance: Tg(KRT5-CHUK)#Rche page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT5-CHUK)#Rche expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CHUK (1147)

  Chuk	(MGI:99484)

• Tg(KRT5-CHUK)#Rche expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  cattle	KRT5 (281268)

• Mutation details: The bovine promoter drives epithelial cell-specific expression of the human cDNA. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:142630)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:142630 Lomada D, et al., Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells. J Immunol. 2007 Jan 15;178(2):829-37
• All: 4 reference(s)