Ntf3^tm2.1Jae
Targeted Allele Detail

Summary

• Symbol: Ntf3^tm2.1Jae
• Name: neurotrophin 3; targeted mutation 2.1, Rudolf Jaenisch
• MGI ID: MGI:5426960
• Synonyms: Nt-3^1lox, Ntf3^-
• Gene: Ntf3 Location: Chr6:126078375-126143703 bp, - strand Genetic Position: Chr6, 60.45 cM
• Alliance: Ntf3^tm2.1Jae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:52951
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Mice expressing the Ntf3^tm2Jae allele were crossed to cre-expressing mice to delete exon 2 from the germline. (J:52951, J:182750)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ntf3 Mutation: 24 strains or lines available

References

• Original: J:52951 Bates B, et al., Neurotrophin-3 is required for proper cerebellar development. Nat Neurosci. 1999 Feb;2(2):115-7
• All: 2 reference(s)