Omp^{tm12.1(cre/ERT2)Mom}
Targeted Allele Detail

Summary

• Symbol: Omp^{tm12.1(cre/ERT2)Mom}
• Name: olfactory marker protein; targeted mutation 12.1, Peter Mombaerts
• MGI ID: MGI:5426991
• Synonyms: OMP-CreERT2
• Gene: Omp Location: Chr7:97792566-97794654 bp, - strand Genetic Position: Chr7, 53.59 cM
• Alliance: Omp^{tm12.1(cre/ERT2)Mom} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:264138
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Inducible, Null/knockout, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Omp^{tm12.1(cre/ERT2)Mom} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Omp (MGI:97436)

• Mutation details: The endogenous coding sequence was replaced by cre/ERT2 and the FRT-flanked neomycin resistance cassette was recombined out through breeding to a transgenic mouse expressing germline FLP1 recombinase. (J:264138)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Omp (mouse) Summary of all recombinase alleles driven by Omp. Comparative matrix view of recombinase activities Alliance mouse Omp gene page

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Omp Mutation: 27 strains or lines available

References

• Original: J:264138 Holl AM, Survival of mature mouse olfactory sensory neurons labeled genetically perinatally. Mol Cell Neurosci. 2018;88:258-269
• All: 1 reference(s)