Rybp^tm1Mvi
Targeted Allele Detail

Summary

• Symbol: Rybp^tm1Mvi
• Name: RING1 and YY1 binding protein; targeted mutation 1, Miguel Vidal
• MGI ID: MGI:5427016
• Synonyms: RYBP^f
• Gene: Rybp Location: Chr6:100205526-100264319 bp, - strand Genetic Position: Chr6, 46.62 cM, cytoband E1
• Alliance: Rybp^tm1Mvi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183700
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3-5 are flanked with loxP sites. An adjacent PGK-neo selection cassette, flanked by frt sites, was removed via Flp-mediated recombination. (J:236205)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rybp Mutation: 45 strains or lines available

References

• Original: J:183700 Hisada K, et al., RYBP represses endogenous retroviruses and preimplantation- and germ line-specific genes in mouse embryonic stem cells. Mol Cell Biol. 2012 Mar;32(6):1139-49
• All: 3 reference(s)