Cspg4^tm1Ychan
Targeted Allele Detail

Summary

• Symbol: Cspg4^tm1Ychan
• Name: chondroitin sulfate proteoglycan 4; targeted mutation 1, Yunchao Chang
• MGI ID: MGI:5427105
• Gene: Cspg4 Location: Chr9:56772388-56807154 bp, + strand Genetic Position: Chr9, 30.32 cM
• Alliance: Cspg4^tm1Ychan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184220
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 2. (J:184220)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cspg4 Mutation: 101 strains or lines available

References

• Original: J:184220 Chang Y, et al., Ablation of NG2 proteoglycan leads to deficits in brown fat function and to adult onset obesity. PLoS One. 2012;7(1):e30637
• All: 4 reference(s)