Kif17^tm1Noh
Targeted Allele Detail

Summary

• Symbol: Kif17^tm1Noh
• Name: kinesin family member 17; targeted mutation 1, Nobutaka Hirokawa
• MGI ID: MGI:5427632
• Gene: Kif17 Location: Chr4:137989562-138029284 bp, + strand Genetic Position: Chr4, 70.07 cM, cytoband D3
• Alliance: Kif17^tm1Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174822
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 4 was replaced with a poly (A)-less PGK-neo cassette. Western blot analysis confirmed the absence of protein expression in the brain. (J:174822)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif17 Mutation: 35 strains or lines available

References

• Original: J:174822 Yin X, et al., Molecular motor KIF17 is fundamental for memory and learning via differential support of synaptic NR2A/2B levels. Neuron. 2011 Apr 28;70(2):310-25
• All: 2 reference(s)