Tg(Col1a1-Mir34c)#Kry
Transgene Detail

Summary

• Symbol: Tg(Col1a1-Mir34c)#Kry
• Name: transgene insertion, Gerard Karsenty
• MGI ID: MGI:5427917
• Synonyms: alpha1(I) miR-34c
• Transgene: Tg(Col1a1-Mir34c)#Kry Location: unknown
• Alliance: Tg(Col1a1-Mir34c)#Kry page

Decreased bone mass in Tg(Col1a1-Mir34c)#Kry/0 mice

Show the 2 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Col1a1-Mir34c)#Kry expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir34c (MGI:3619365)

• Mutation details: The mouse promoter drives osteoblast-specific expression of the mouse microRNA. The pound symbol (#) is used when no lines are specified and/or lines are pooled. (J:185130)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:185130 Wei J, et al., miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol. 2012 May 14;197(4):509-21
• All: 1 reference(s)