Dhx36^tm1.1Pmt
Targeted Allele Detail

Summary

• Symbol: Dhx36^tm1.1Pmt
• Name: DEAH-box helicase 36; targeted mutation 1.1, Patrick Matthias
• MGI ID: MGI:5427959
• Synonyms: RHAU^delta
• Gene: Dhx36 Location: Chr3:62375434-62414425 bp, - strand Genetic Position: Chr3, 29.97 cM
• Alliance: Dhx36^tm1.1Pmt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185179
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/Ola

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 8. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 8. Cre-mediated recombination removed exon 8 and the neo cassette. (J:185179)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dhx36 Mutation: 53 strains or lines available

References

• Original: J:185179 Lai JC, et al., The DEAH-box helicase RHAU is an essential gene and critical for mouse hematopoiesis. Blood. 2012 May 3;119(18):4291-300
• All: 2 reference(s)