Tmsb4x^tm1.2Chen
Targeted Allele Detail

Summary

• Symbol: Tmsb4x^tm1.2Chen
• Name: thymosin, beta 4, X chromosome; targeted mutation 1.2, Ju Chen
• MGI ID: MGI:5427990
• Synonyms: tbeta4^f
• Gene: Tmsb4x Location: ChrX:165990089-165992311 bp, - strand Genetic Position: ChrX, 78.28 cM
• Alliance: Tmsb4x^tm1.2Chen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185264
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Flp-mediated recombination of frt sites resulted in the removal of a neo cassette, leaving loxP sites that flank exon 2. (J:185264)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmsb4x Mutation: 12 strains or lines available

References

• Original: J:185264 Banerjee I, et al., Thymosin beta 4 is dispensable for murine cardiac development and function. Circ Res. 2012 Feb 3;110(3):456-64
• All: 2 reference(s)