Tg(FOXJ1-cre)F14Htzm
Transgene Detail

Summary

• Symbol: Tg(FOXJ1-cre)F14Htzm
• Name: transgene insertion F14, Michael J Holtzman
• MGI ID: MGI:5428030
• Synonyms: FOXJ1-Cre
• Transgene: Tg(FOXJ1-cre)F14Htzm Location: unknown
• Alliance: Tg(FOXJ1-cre)F14Htzm page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(FOXJ1-cre)F14Htzm expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  FOXJ1 (2302)

  Foxj1

  (MGI:1347474)

• Mutation details: This transgene expresses Cre recombinase under the control of 1.2kb of the human FOXJ1 promoter. Cre expression occurs in ciliated epithelial cells present in the pulmonary airways, the choroid plexus, ependyma, oviduct and testis. This record represents line F26, which has the highest expression of Cre in the lung compared to the two other founder lines, F14 and F24. (J:136610)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	FOXJ1 (human) Summary of all recombinase alleles driven by FOXJ1. Alliance human FOXJ1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:136610 Zhang Y, et al., A transgenic FOXJ1-Cre system for gene inactivation in ciliated epithelial cells. Am J Respir Cell Mol Biol. 2007 May;36(5):515-9
• All: 9 reference(s)