Il21^tm1Nutt
Targeted Allele Detail

Summary

• Symbol: Il21^tm1Nutt
• Name: interleukin 21; targeted mutation 1, Stephen L Nutt
• MGI ID: MGI:5428706
• Synonyms: Il21^GFP
• Gene: Il21 Location: Chr3:37276908-37286785 bp, - strand Genetic Position: Chr3, 18.36 cM, cytoband B
• Alliance: Il21^tm1Nutt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185372
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An expression cassette was inserted into intron 2. The expression cassette contains (5' to 3') an FRT site, splice acceptor, IRES, EGFP, neo cassette and FRT site. (J:185372)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il21 Mutation: 42 strains or lines available

References

• Original: J:185372 Luthje K, et al., The development and fate of follicular helper T cells defined by an IL-21 reporter mouse. Nat Immunol. 2012 May;13(5):491-8
• All: 8 reference(s)