Tg(ACTA1-SSPN)3.0Rcros
Transgene Detail

Summary

• Symbol: Tg(ACTA1-SSPN)3.0Rcros
• Name: transgene insertion 3.0, Rachelle H Crosbie-Watson
• MGI ID: MGI:5428721
• Synonyms: 3.0 SSPN-Tg
• Transgene: Tg(ACTA1-SSPN)3.0Rcros Location: unknown
• Alliance: Tg(ACTA1-SSPN)3.0Rcros page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTA1-SSPN)3.0Rcros expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SSPN (8082)

  Sspn	(MGI:1353511)

• Tg(ACTA1-SSPN)3.0Rcros expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  ACTA1 (58)

  Acta1

  (MGI:87902)

• Mutation details: The human promoter drives skeletal muscle-specific expression of the human cDNA. Three lines were established with 0.5, 1.5 and 3 times wild-type expression levels (named 0.5, 1.5 and 3.0, respectively). (J:185346)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:185346 Marshall JL, et al., Sarcospan-dependent Akt activation is required for utrophin expression and muscle regeneration. J Cell Biol. 2012 Jun 25;197(7):1009-27
• All: 4 reference(s)