Id2^tm1Xdz
Targeted Allele Detail

Summary

• Symbol: Id2^tm1Xdz
• Name: inhibitor of DNA binding 2; targeted mutation 1, Xu-Dong Zhao
• MGI ID: MGI:5428940
• Synonyms: Id2^f, Id2Flox, Id2^L
• Gene: Id2 Location: Chr12:25143798-25146091 bp, - strand Genetic Position: Chr12, 8.57 cM, cytoband B
• Alliance: Id2^tm1Xdz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185426
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exons 1 and 2 floxed. (J:185426)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Id2 Mutation: 21 strains or lines available

References

• Original: J:185426 Niola F, et al., Id proteins synchronize stemness and anchorage to the niche of neural stem cells. Nat Cell Biol. 2012 May;14(5):477-87
• All: 24 reference(s)