Zeb1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Zeb1^m1Btlr
• Name: zinc finger E-box binding homeobox 1; mutation 1, Bruce Beutler
• MGI ID: MGI:5428990
• Synonyms: cellophane
• Gene: Zeb1 Location: Chr18:5591860-5775467 bp, + strand Genetic Position: Chr18, 4.42 cM
• Alliance: Zeb1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU-induced a T to A transversion at position 2725 in exon 7 of 8 exons. This mutation results in the conversion of a tyrosine codon at position 902 to a premature stop codon. (J:185495)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zeb1 Mutation: 65 strains or lines available

References

• Original: J:185495 Arnold CN, et al., A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12286-93
• All: 2 reference(s)