Pip4k2b^{Gt(OST341064)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Pip4k2b^{Gt(OST341064)Lex}
• Name: phosphatidylinositol-5-phosphate 4-kinase, type II, beta; gene trap OST341064, Lexicon Genetics
• MGI ID: MGI:5428995
• Gene: Pip4k2b Location: Chr11:97605983-97635530 bp, - strand Genetic Position: Chr11, 61.07 cM
• Alliance: Pip4k2b^{Gt(OST341064)Lex} page

Mutation origin

• Mutant Cell Line: OST341064
• Germline Transmission: Earliest citation of germline transmission: J:185494
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector inserted in the first intron of the gene (accession NM_054051.1). No endogenous PIP5K2B transcript was detected in homozygous (-/-) tissues by RT-PCR analysis. (J:185494)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pip4k2b Mutation: 34 strains or lines available

References

• Original: J:185494 Brommage R, et al., High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes. Obesity (Silver Spring). 2008 Oct;16(10):2362-7
• All: 1 reference(s)