Mc4r^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Mc4r^tm1Lex
• Name: melanocortin 4 receptor; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:5428998
• Gene: Mc4r Location: Chr18:66990776-66993558 bp, - strand Genetic Position: Chr18, 39.72 cM, cytoband E1
• Alliance: Mc4r^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185494
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 1 was deleted. (J:185494)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mc4r Mutation: 48 strains or lines available

References

• Original: J:185494 Brommage R, et al., High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes. Obesity (Silver Spring). 2008 Oct;16(10):2362-7
• All: 2 reference(s)