Ksr2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Ksr2^tm1Lex
• Name: kinase suppressor of ras 2; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:5429039
• Gene: Ksr2 Location: Chr5:117552067-117906061 bp, + strand Genetic Position: Chr5, 56.88 cM
• Alliance: Ksr2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185494
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 15-16 were deleted. (J:185494)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ksr2 Mutation: 42 strains or lines available

References

• Original: J:185494 Brommage R, et al., High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes. Obesity (Silver Spring). 2008 Oct;16(10):2362-7
• All: 4 reference(s)