Ak8^{Gt(OST16378)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Ak8^{Gt(OST16378)Lex}
• Name: adenylate kinase 8; gene trap OST16378, Lexicon Genetics
• MGI ID: MGI:5429197
• Gene: Ak8 Location: Chr2:28590176-28703177 bp, + strand Genetic Position: Chr2, 19.38 cM
• Alliance: Ak8^{Gt(OST16378)Lex} page

Mutation origin

• Mutant Cell Line: OST16378
• Germline Transmission: Earliest citation of germline transmission: J:185566
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Hypomorph, Reporter)
• Mutation: Insertion of gene trap vector
• A gene trap vector inserted into intron 5. (J:185566)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ak8 Mutation: 25 strains or lines available

References

• Original: J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
• All: 1 reference(s)