Celsr2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Celsr2^tm1Lex
• Name: cadherin, EGF LAG seven-pass G-type receptor 2; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:5429210
• Gene: Celsr2 Location: Chr3:108298167-108323383 bp, - strand Genetic Position: Chr3, 47.02 cM
• Alliance: Celsr2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185566
• Parent Cell Line: Lex-2 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Deletion of coding exons 21-33. (J:185566)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Celsr2 Mutation: 114 strains or lines available

References

• Original: J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
• All: 1 reference(s)