Tg(SNCA)ARyot
Transgene Detail

Summary

• Symbol: Tg(SNCA)ARyot
• Name: transgene insertion A, Ryosuke Takahashi
• MGI ID: MGI:5429214
• Synonyms: alpha-syn BAC tg
• Transgene: Tg(SNCA)ARyot Location: unknown
• Alliance: Tg(SNCA)ARyot page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(SNCA)ARyot expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Mutation details: The transgene consists of the PAC AF163864 and BAC AC097478 and contains 28 kb fo the 5' and 50 kb of the 3' flanking sequences in addition to the entire human gene. Lines A and B (8 and 1 copy, respectively) were generated. (J:185434)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:185434 Yamakado H, et al., alpha-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion. Neurosci Res. 2012 Jun;73(2):173-7
• All: 7 reference(s)