Kcnb2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Kcnb2^tm1Lex
• Name: potassium voltage gated channel, Shab-related subfamily, member 2; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:5429909
• Synonyms: Kv2.2 KO, LEXKO-1551
• Gene: Kcnb2 Location: Chr1:15357478-15793974 bp, + strand Genetic Position: Chr1, 4.5 cM
• Alliance: Kcnb2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The last coding exon (with the stop codon) was targeted (XM_976837). Disruption of the target gene was confirmed by Southern hybridization analysis. (J:82809)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Kcnb2 Mutation: 40 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 10 reference(s)