b2b1470Clo
Chemically induced Allele Detail

Summary

• Symbol: b2b1470Clo
• Name: Mutant line 1470; Bench to Bassinet Program (B2B/CVDC), mutation 1470 Cecilia Lo
• MGI ID: MGI:5430054
• Synonyms: LAMP
• Gene: b2b1470Clo Location: unknown
• Alliance: b2b1470Clo page

1470-002-NA displays cleft palate and lip

Show the 6 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. (J:175213)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any b2b1470Clo Mutation: 1 strain or line available

Notes

Summative Diagnosis:
Non-Cardiac Phenotype: Cleft palate and facial cleft, limb defects comprising polydactyly/syndactyly/oligodactyly

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
4103	Polydactyly
4174	Syndactyly
4876	Cleft palate

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)