Zp3r^tm1Osb
Targeted Allele Detail

Summary

• Symbol: Zp3r^tm1Osb
• Name: zona pellucida 3 receptor; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:5430162
• Gene: Zp3r Location: Chr1:130504450-130557358 bp, - strand Genetic Position: Chr1, 56.89 cM, cytoband E-F
• Alliance: Zp3r^tm1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185779
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 4 was replaced with a floxed neo cassette. Western blot analysis confirmed the absence of protein expression. (J:185779)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Zp3r Mutation: 37 strains or lines available

References

• Original: J:185779 Muro Y, et al., Function of the acrosomal matrix: zona pellucida 3 receptor (ZP3R/sp56) is not essential for mouse fertilization. Biol Reprod. 2012 Jan;86(1):1-6
• All: 1 reference(s)