Taf7^tm1.1Dss
Targeted Allele Detail

Summary

• Symbol: Taf7^tm1.1Dss
• Name: TATA-box binding protein associated factor 7; targeted mutation 1.1, Dinah S Singer
• MGI ID: MGI:5430372
• Gene: Taf7 Location: Chr18:37773544-37777257 bp, - strand Genetic Position: Chr18, 19.54 cM
• Alliance: Taf7^tm1.1Dss page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185745
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of the coding sequence. An FRT- and loxP-flanked neo cassette was inserted into the 3' UTR. Cre-mediated recombination removed the coding sequence and neo cassette. (J:185745)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taf7 Mutation: 19 strains or lines available

References

• Original: J:185745 Gegonne A, et al., The general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells. Mol Cell Biol. 2012 May;32(10):1984-97
• All: 2 reference(s)