Tg(INPP5B)CNbm
Transgene Detail

Summary

• Symbol: Tg(INPP5B)CNbm
• Name: transgene insertion C, Robert L Nussbaum
• MGI ID: MGI:5430746
• Transgene: Tg(INPP5B)CNbm Location: unknown
• Alliance: Tg(INPP5B)CNbm page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(INPP5B)CNbm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  INPP5B (3633)

  Inpp5b

  (MGI:103257)

• Mutation details: The transgene consisted of the human BAC RP11-431J04. Lines C, F and G were generated of which line C contains multiple tandem copies. (J:185879)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:185879 Bothwell SP, et al., Mouse model for Lowe syndrome/Dent Disease 2 renal tubulopathy. J Am Soc Nephrol. 2011 Mar;22(3):443-8
• All: 2 reference(s)