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Tg(GFAP-Fig4)#Mm
Transgene Detail
Summary
Symbol: Tg(GFAP-Fig4)#Mm
Name: transgene insertion, Miriam H Meisler
MGI ID: MGI:5431007
Transgene: Tg(GFAP-Fig4)#Mm  Location: unknown  
Alliance: Tg(GFAP-Fig4)#Mm page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(GFAP-Fig4)#Mm expresses 1 gene
 
Mutation detailsThe human GFAP promoter composed of 2.2 kb of upstream sequence ant 46 bp of exon 1 in which the ATG start sequence was mutated to TTG wis used to drive expression of a mouse Fig4 cDNA. (J:185989)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:185989 Ferguson CJ, et al., Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. Hum Mol Genet. 2012 Aug 15;21(16):3525-34
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory