About   Help   FAQ
Tg(GFAP-Fig4)#Mm
Transgene Detail
Summary
Symbol: Tg(GFAP-Fig4)#Mm
Name: transgene insertion, Miriam H Meisler
MGI ID: MGI:5431007
Transgene: Tg(GFAP-Fig4)#Mm  Location: unknown  
Alliance: Tg(GFAP-Fig4)#Mm page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(GFAP-Fig4)#Mm expresses 1 gene
 
Mutation detailsThe human GFAP promoter composed of 2.2 kb of upstream sequence ant 46 bp of exon 1 in which the ATG start sequence was mutated to TTG wis used to drive expression of a mouse Fig4 cDNA. (J:185989)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:185989 Ferguson CJ, et al., Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. Hum Mol Genet. 2012 Aug 15;21(16):3525-34
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory