Del(16App-Runx1)5Yah
Targeted Allele Detail

Summary

• Symbol: Del(16App-Runx1)5Yah
• Name: deletion, Chr 16, Yann Herault 5
• MGI ID: MGI:5431211
• Synonyms: Del5Yah, Ms5Yah
• Gene: Del(16App-Runx1)5Yah Location: Chr16:84749554-92622962 bp Genetic Position: Chr16, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185269
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Intergenic deletion, Intragenic deletion Del(16App-Runx1)5Yah involves 149 genes/genome features (Gm27295, Gm23587, Gm22933 ...) View all Mutation details: Targeted meiotic recombination (TAMERE) removed the genomic sequence, including 46 genes, between loxP sites inserted into App and Runx1. (J:185269)

Generation of the Del(16App-Runx1)5Yah mouse model

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(16App-Runx1)5Yah Mutation: 0 strains or lines available

References

• Original: J:185269 Raveau M, et al., The app-runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a down syndrome mouse model. PLoS Genet. 2012 May;8(5):e1002724
• All: 2 reference(s)