Dll1^tm1.1Mjo
Targeted Allele Detail

Summary

• Symbol: Dll1^tm1.1Mjo
• Name: delta like canonical Notch ligand 1; targeted mutation 1.1, Michael J Owen
• MGI ID: MGI:5431502
• Gene: Dll1 Location: Chr17:15587616-15597134 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dll1^tm1.1Mjo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186213
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exons 3 and 4. (J:90630)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dll1 Mutation: 46 strains or lines available

References

• Original: J:186213 Sparrow DB, et al., A mechanism for gene-environment interaction in the etiology of congenital scoliosis. Cell. 2012 Apr 13;149(2):295-306
• All: 3 reference(s)