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Med13tm1Eno
Targeted Allele Detail
Summary
Symbol: Med13tm1Eno
Name: mediator complex subunit 13; targeted mutation 1, Eric N Olson
MGI ID: MGI:5431516
Synonyms: Med13fl
Gene: Med13  Location: Chr11:86157859-86248422 bp, - strand  Genetic Position: Chr11, 51.75 cM
Alliance: Med13tm1Eno page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186193
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 7. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 8. (J:186193)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Med13 Mutation:  89 strains or lines available
References
Original:  J:186193 Grueter CE, et al., A cardiac microRNA governs systemic energy homeostasis by regulation of MED13. Cell. 2012 Apr 27;149(3):671-83
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory