Sptbn1^tm1.1Mnr
Targeted Allele Detail

Summary

• Symbol: Sptbn1^tm1.1Mnr
• Name: spectrin beta, non-erythrocytic 1; targeted mutation 1.1, Matthew N Rasband
• MGI ID: MGI:5431637
• Synonyms: SPNB2^fl
• Gene: Sptbn1 Location: Chr11:30049395-30218175 bp, - strand Genetic Position: Chr11, 17.44 cM
• Alliance: Sptbn1^tm1.1Mnr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186168
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 was floxed and an FRT-flanked neo cassette was removed by flp-mediated recombination. (J:186168)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sptbn1 Mutation: 139 strains or lines available

References

• Original: J:186168 Galiano MR, et al., A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly. Cell. 2012 May 25;149(5):1125-39
• All: 10 reference(s)