Tg(tetO-LAMA5)1Jhm
Transgene Detail
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| Symbol: |
Tg(tetO-LAMA5)1Jhm |
| Name: |
transgene insertion 1, Jeffrey H Miner |
| MGI ID: |
MGI:5431872 |
| Synonyms: |
tetO-LA5 |
| Transgene: |
Tg(tetO-LAMA5)1Jhm Location: unknown
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| Alliance: |
Tg(tetO-LAMA5)1Jhm page
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: The full-length human laminin alpha5 (LA5; LAMA5) cDNA with a bovine growth hormone polyadenylation signal was placed under control of the tetracycline resistance-operon tetO (7 copies) and the CMV minimal promoter. The construct was microinjected into single-celled C57BL/6NTac embryos. 15 potential founders were obtained. 2 expressed the transgene in the expected pattern, and one of these was analyzed further.
(J:185850)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:185850 Goldberg S, et al., Maintenance of glomerular filtration barrier integrity requires laminin alpha5. J Am Soc Nephrol. 2010 Apr;21(4):579-86 |
| All: |
3 reference(s) |
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Analysis Tools
