Drp2^tm1.1Brp
Targeted Allele Detail

Summary

• Symbol: Drp2^tm1.1Brp
• Name: dystrophin related protein 2; targeted mutation 1.1, Peter J Brophy
• MGI ID: MGI:5431939
• Synonyms: Drp2^fl
• Gene: Drp2 Location: ChrX:133305300-133357322 bp, + strand Genetic Position: ChrX, 56.18 cM, cytoband E3
• Alliance: Drp2^tm1.1Brp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:185953
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exon 4 floxed. (J:185953)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Drp2 Mutation: 13 strains or lines available

References

• Original: J:185953 Sherman DL, et al., Drp2 and periaxin form cajal bands with dystroglycan but have distinct roles in schwann cell growth. J Neurosci. 2012 Jul 4;32(27):9419-28
• All: 1 reference(s)