Smarcc2^tm1.1Grc
Targeted Allele Detail

Summary

• Symbol: Smarcc2^tm1.1Grc
• Name: SWI/SNF related BAF chromatin remodeling complex subunit C2; targeted mutation 1.1, Gerald R Crabtree
• MGI ID: MGI:5431983
• Gene: Smarcc2 Location: Chr10:128295117-128326351 bp, + strand Genetic Position: Chr10, 76.59 cM
• Alliance: Smarcc2^tm1.1Grc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin cassette flanked by loxP sites was introduced to intron 2 and a loxP site was inserted in intron 3. Cre-mediated recombination removed the neo cassette and exon 3. This deletion creates a protein frame shift after amino acid 77. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Smarcc2 Mutation: 56 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)