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Trim72tm1Ygko
Targeted Allele Detail
Summary
Symbol: Trim72tm1Ygko
Name: tripartite motif-containing 72; targeted mutation 1, Young-Gyu Ko
MGI ID: MGI:5432128
Synonyms: MG53-
Gene: Trim72  Location: Chr7:127603121-127610205 bp, + strand  Genetic Position: Chr7, 69.89 cM
Alliance: Trim72tm1Ygko page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186368
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 through 3 were replaced with a neo cassette. Western blot analysis confirmed the absence of protein expression in skeletal muscle. (J:186368)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trim72 Mutation:  34 strains or lines available
References
Original:  J:186368 Lee CS, et al., TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1. Cell Death Differ. 2010 Aug;17(8):1254-65
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory