Fam20b^{Gt(GST_4283_D8)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Fam20b^{Gt(GST_4283_D8)Lex}
• Name: FAM20B, glycosaminoglycan xylosylkinase; gene trap GST_4283_D8, Lexicon Genetics
• MGI ID: MGI:5432371
• Synonyms: Fam20b^{Gt(GST_4283_D8)Lex1}
• Gene: Fam20b Location: Chr1:156506102-156546656 bp, - strand Genetic Position: Chr1, 67.71 cM
• Alliance: Fam20b^{Gt(GST_4283_D8)Lex} page

Mutation origin

• Mutant Cell Line: GST_4283_D8
• Germline Transmission: Earliest citation of germline transmission: J:186384
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Gene trap vector VICTR48 insertion in intron 1 resulted in disruption of this gene. (J:186384)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam20b Mutation: 29 strains or lines available

Notes

This Lexicon Genetics gene trap mutation was generated in either Lex-1 or Lex-2 (129S5/SvEvBrd) parental ES cell line. The specific ES cell line in which this mutation was made is not specified.

References

• Original: J:186384 Vogel P, et al., Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice. Vet Pathol. 2012 Nov;49(6):998-1017
• All: 2 reference(s)