Fam20c^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Fam20c^tm1Lex
• Name: FAM20C, golgi associated secretory pathway kinase; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:5432377
• Gene: Fam20c Location: Chr5:138740836-138795818 bp, + strand Genetic Position: Chr5, 77.19 cM
• Alliance: Fam20c^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186384
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 including the start codon and exon 2 were replaced by a lacZ/floxed neo cassette. (J:186384)

Expression

In Structures Affected by this Mutation:

25 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fam20c Mutation: 26 strains or lines available

References

• Original: J:186384 Vogel P, et al., Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice. Vet Pathol. 2012 Nov;49(6):998-1017
• All: 2 reference(s)