Ddit4^tm1.1Sinc
Targeted Allele Detail

Summary

• Symbol: Ddit4^tm1.1Sinc
• Name: DNA-damage-inducible transcript 4; targeted mutation 1.1, Andrew Sinclair
• MGI ID: MGI:5432482
• Gene: Ddit4 Location: Chr10:59785497-59787592 bp, - strand Genetic Position: Chr10, 29.66 cM, cytoband B3
• Alliance: Ddit4^tm1.1Sinc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186462
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. A neo cassette with a 3' loxP site was inserted downstream of exon 3. Cre-mediated recombination removed the coding sequence and the neo cassette. (J:186462)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddit4 Mutation: 18 strains or lines available

References

• Original: J:186462 Notini AJ, et al., Redd1 is a novel marker of testis development but is not required for normal male reproduction. Sex Dev. 2012;6(5):223-30
• All: 1 reference(s)