Calhm1^tm1Geno
Targeted Allele Detail

Summary

• Symbol: Calhm1^tm1Geno
• Name: calcium homeostasis modulator 1; targeted mutation 1, Genoway
• MGI ID: MGI:5432529
• Gene: Calhm1 Location: Chr19:47129474-47132613 bp, - strand Genetic Position: Chr19, 39.36 cM
• Alliance: Calhm1^tm1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186424
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 552 bp of coding sequence, including the translation initiation site and the entire exon 1, were deleted. (J:186424)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Calhm1 Mutation: 13 strains or lines available

References

• Original: J:186424 Ma Z, et al., Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):E1963-71
• All: 16 reference(s)