Sult2b1^tm1Rus
Targeted Allele Detail

Summary

• Symbol: Sult2b1^tm1Rus
• Name: sulfotransferase family, cytosolic, 2B, member 1; targeted mutation 1, David Russell
• MGI ID: MGI:5432568
• Gene: Sult2b1 Location: Chr7:45379405-45409096 bp, - strand Genetic Position: Chr7, 29.47 cM
• Alliance: Sult2b1^tm1Rus page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186536
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace the seven coding exons the sulfotransferase 2B1 (Sult2b1) gene with a cassette containing the neomycin resistance gene and Cre recombinase gene under the control of angiotensin-converting enzyme promoter. This cassette was flanked by loxP sites. Cre-mediated recombination during spermatogenesis removed the inserted cassette leaving one loxP site. (J:186536)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sult2b1 Mutation: 25 strains or lines available

References

• Original: J:186536 Russell D, Targeted mutation of the Sult2b1 gene in mice. MGI Direct Data Submission. 2012
• All: 8 reference(s)