Rasgrp4^tm1(cre)Rls
Targeted Allele Detail

Summary

• Symbol: Rasgrp4^tm1(cre)Rls
• Name: RAS guanyl releasing protein 4; targeted mutation 1, Richard L Stevens
• MGI ID: MGI:5432899
• Gene: Rasgrp4 Location: Chr7:28834358-28853386 bp, + strand Genetic Position: Chr7, 16.94 cM, cytoband B1
• Alliance: Rasgrp4^tm1(cre)Rls page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186519
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A cre-neo cassette replaced exons 1 through 8. (J:186519)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasgrp4 Mutation: 41 strains or lines available

References

• Original: J:186519 Adachi R, et al., Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis. J Biol Chem. 2012 Jun 8;287(24):20047-55
• All: 1 reference(s)