Tmem107^schlei
Chemically induced Allele Detail

Summary

• Symbol: Tmem107^schlei
• Name: transmembrane protein 107; schlei
• MGI ID: MGI:5433051
• Gene: Tmem107 Location: Chr11:68961635-68964119 bp, + strand Genetic Position: Chr11, 42.35 cM, cytoband B3
• Alliance: Tmem107^schlei page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced an A to G transition that results in the amino acid substitution of glycine for glutamic acid at position 125 (E125G) within the fourth transmembrane domain. (J:186552)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	38 assay results
In Structures Affected by this Mutation:	16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem107 Mutation: 21 strains or lines available

References

• Original: J:186552 Christopher KJ, et al., Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling. Dev Biol. 2012 Aug 15;368(2):382-92
• All: 4 reference(s)