Litaftm1.1Ics
Targeted Allele Detail
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| Symbol: |
Litaftm1.1Ics |
| Name: |
LPS-induced TN factor; targeted mutation 1.1, Mouse Clinical Institute |
| MGI ID: |
MGI:5433218 |
| Gene: |
Litaf Location: Chr16:10777137-10810985 bp, - strand Genetic Position: Chr16, 6.28 cM, cytoband B1-B3
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| Alliance: |
Litaftm1.1Ics page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:186411
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Cre-mediated recombination removed the floxed exon 2. Western blot analysis confirmed the absence of protein expression in nerves.
(J:186411)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Litaf Mutation: |
14 strains or lines available
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| Original: |
J:186411 Somandin C, et al., LITAF (SIMPLE) regulates Wallerian degeneration after injury but is not essential for peripheral nerve development and maintenance: Implications for Charcot-Marie-Tooth disease. Glia. 2012 Oct;60(10):1518-28 |
| All: |
1 reference(s) |
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Analysis Tools
