Ly75tm1.1(HBEGF/EGFP)Ksat
Targeted Allele Detail
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Symbol: |
Ly75tm1.1(HBEGF/EGFP)Ksat |
Name: |
lymphocyte antigen 75; targeted mutation 1.1, Katsuaki Sato |
MGI ID: |
MGI:5433322 |
Synonyms: |
Cd205dtr |
Gene: |
Ly75 Location: Chr2:60122447-60213617 bp, - strand Genetic Position: Chr2, 34.54 cM
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Alliance: |
Ly75tm1.1(HBEGF/EGFP)Ksat page
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Germline Transmission: |
Earliest citation of germline transmission:
J:186395
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Inserted expressed sequence, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Ly75tm1.1(HBEGF/EGFP)Ksat expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
HBEGF (1839) |
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Mutation details: A human diphtheria toxin receptor (HBEGF or DTR) with a 5' IRES was fused to EGFP and inserted into the 3' UTR. A self-excising neo cassette removed itself.
(J:186395)
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Generation of the Ly75tm1.1(HBEGF/EGFP)Ksat allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ly75 Mutation: |
78 strains or lines available
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Original: |
J:186395 Fukaya T, et al., Conditional ablation of CD205+ conventional dendritic cells impacts the regulation of T-cell immunity and homeostasis in vivo. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11288-93 |
All: |
1 reference(s) |
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