Ect2^tm1.2Cjd
Targeted Allele Detail

Summary

• Symbol: Ect2^tm1.2Cjd
• Name: ect2 oncogene; targeted mutation 1.2, Channing J Der
• MGI ID: MGI:5433509
• Synonyms: Ect2^-
• Gene: Ect2 Location: Chr3:27151371-27207971 bp, - strand Genetic Position: Chr3, 10.82 cM, cytoband B
• Alliance: Ect2^tm1.2Cjd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:186780
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site and FRT flanked neo cassette were inserted into intron 7 and a loxP site was inserted into intron 8 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exon 8. (J:186780)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ect2 Mutation: 56 strains or lines available

References

• Original: J:186780 Cook DR, et al., The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration. Genes Cancer. 2011 Oct;2(10):932-42
• All: 2 reference(s)