Tg(Vil-SLC3A2)HEMerl
Transgene Detail

Summary

• Symbol: Tg(Vil-SLC3A2)HEMerl
• Name: transgene insertion HE, Didier Merlin
• MGI ID: MGI:5433607
• Synonyms: CD98 Tg, Tg-HE
• Transgene: Tg(Vil-SLC3A2)HEMerl Location: unknown
• Alliance: Tg(Vil-SLC3A2)HEMerl page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Vil-SLC3A2)HEMerl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SLC3A2 (6520)

  Slc3a2

  (MGI:96955)

• Mutation details: The mouse promoter drives expression of the human cDNA in intestinal epithelial cells. Three founder lines were established. Line HE is the high expressor line. (J:173946)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:173946 Nguyen HT, et al., CD98 expression modulates intestinal homeostasis, inflammation, and colitis-associated cancer in mice. J Clin Invest. 2011 May 2;121(5):1733-47
• All: 4 reference(s)